|
KMID : 0361020070500050420
|
|
Korean Journal of Otolaryngology - Head and Neck Surgery
2007 Volume.50 No. 5 p.420 ~ p.425
|
|
|
Clinical Manifestation and Differential Diagnosis of Thyroid Follicular Neoplasm
|
|
Tae Kyung
Lee Yong-Seop
Lee Hyung-Seok
Ahn You-Hern
Jeon Sung-Ha
Kim Dong-Sun
Choi Woong-Hwan
Park Dong-Woo
|
|
|
Abstract
|
|
|
Background & Objectives: A preoperative differential diagnosis between follicular adenoma and follicular carcinoma of thyroid is very difficult, and the standard basis for distinction is the presence of capsular and/or vascular invasion. In this study, we analyzed the findings of preoperative tests and clinical features to facilitate the differential diagnosis and treatment of the follicular neoplasm.
Subjects & Methods: A retrospective review of medical records was carried out on 104 patients who had undergone thyroid surgery and had been diagnosed with thyroid follicular adenoma or carcinoma from 1995 through 2004. The final pathologic diagnosis was compared to the various clinical data including the result of fine needle aspiration cytology (FNAC) and ultrasonographic findings.
Results: Of total 104 cases, 82 were follicular adenoma and 22 were follicular carcinoma. The incidence of carcinoma was significantly higher in male than in female. The result of FNAC were divided into 6 cytodiagnostic groups, namely, inadequate, colloid nodule without atypia, colloid nodule with atypia, follicular neoplasm without atypia, follicular neoplasm with atypia, or highly suspicious malignancy. The incidence of carcinoma was significantly higher in the groups with atypia such as colloid nodule with atypia, follicular neoplasm with atypia, and highly suspicious malignancy than in the groups without atypia. The incidence of follicular carcinoma was significantly higher in ill-defined marginal cases. Calcification on ultrasonography also indicated the possibility of malignancy.
Conclusion: The incidence of follicular carcinoma was significantly high in male patients, atypia in FNAC, and ill-defined margin and calcification on ultrasonography.
|
|
|
KEYWORD
|
|
|
Thyroid Neoplasm, Follicular Neoplasm, Follicular carcinoma
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
  
|
|